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SAM-E refers to S-adenosy-L-methionine and it comprises of ATP and amino acid methionine. Technically, SAM-E is involved in the manufacturing of various important compounds in the body. It is found in every cell of the body and naturally, its levels fall with ageing. It is a natural anti-depressant and promotes normal brain cell functions.
Being involved in numerous bodily chemical reactions, SAM-E is essential for healthy nerve functions and cell maintenance. Natural SAM-E supplements are known to affect a number of conditions including Fybromyalgia, depression, liver diseases and osteoarthritis. Some holistic experts believe it offers pain relief without the usual side-effects of aspirin. SAM-E is also known to help in fight against cholestasis, migraines and Gilbert's syndrome.