Celiac - Gluten Sensitive Enteropathy Profile Blood and Saliva Test Kit

Bio Health Labs

Celiac - Gluten Sensitive Enteropathy Profile Blood and Saliva Test Kit Bio Health Labs

Regular price $272.45 $272.45
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Celiac - Gluten Sensitive Enteropathy Profile Blood and Saliva Test Kit

Bio Health Labs

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Regular price $272.45 $272.45
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Ordering the BioHealth test kit is a simple process

1. Purchase the BioHealth test kit from VitaLiving.com. You never have to pay for shipping.

2. Your BioHealth test kit will be mailed to you.

3. You will also be provided with a Free Return Shipping label to send your samples to the lab.

4. Collect your saliva or stool sample as per directions in the test kit.

5. Mail the test kit using the Free Shipping label.

6. Your test results will be emailed to you within 3 weeks.


This screen uses serum to assess total IgA; IgA and IgG to gliadin, a peptide found in gluten; and anti-transglutaminase IgA, a marker for celiac disease within the humoral immune compartment. It also uses a salivary sample to assess the level of secretory immunoglobulin A (sIgA) and the level of salivary IgA to gliadin within the mucosal immune compartment. This test is designed to assess whether an individual is celiac (overt symptoms) or has subclinical gluten intolerance (non-symptomatic, that is without obvious GI symptoms).

The Markers

Total Serum IgA: Total serum IgA is used to qualify the IgA levels for anti-gliadin and anti-transglutaminase and to rule out compromised systemic immunity. Individuals with Selective IgA deficiency may have a clinical or sub-clinical gluten sensitive enteropathy (GSE) with anti-gliadin IgA and anti-transglutaminase IgA reported within normal ranges.

Anti-Gliadin Antibody, IgA: Gliadin IgA is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgA antibodies in human serum. Detection of these antibodies is an aid in the diagnosis of certain gluten sensitive enteropathies such as celiac disease and herpetiformis. Celiac disease or gluten sensitivity enteropathy is a chronic condition whose main features include inflammation and characteristic histological “flattening” of intestinal mucosa resulting in a malabsorption syndrome.

Anti-Gliadin Antibody, IgG: Gliadin IgG is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgG antibodies in human serum. Detection of these antibodies is an aid in the diagnosis of certain gluten sensitive enteropathies such as celiac disease and herpetiformis. Celiac disease or gluten sensitivity enteropathy is a chronic condition whose main features include inflammation and characteristic histological “flattening” of intestinal mucosa resulting in a malabsorption syndrome.

Anti-Transglutaminase, IgA: Human tissue transglutaminase is an enzyme-linked immunosorbent assay (ELISA) for the detection of IgA antibodies to tissue transglutaminase (endomysium) in human serum. Detection of these antibodies is an aid in diagnosis of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis. Celiac disease and dermatitis herpetiformis, two recognized forms of gluten sensitive enteropathy (GSE) are characterized by chronic inflammation of the intestinal mucosa and flattening of the epithelium or positive “villous atrophy.” Intolerance to gluten (gliadin), the protein found primarily in grains such as wheat, rye and barley causes GSE. Patients with celiac disease may suffer from diarrhea, gastrointestinal problems, anemia, fatigue, psychiatric problems and other diverse side effects or they may be asymptomatic. Dermatitis herpetiformis is a skin disease associated with GSE. All GSE patients have an increased risk of lymphoma. A gluten-free diet controls GSE and associated risks.

Salivary Anti-Gliadin Antibody, IgA: An elevation in this antibody is evidence of mucotoxic reaction to the gliadin polypeptide within the digestive tract. Depending on the overall health of the mucosal barrier and whether or not the gut is “leaky”, gluten sensitive enteropathies can show up either in the mucosal compartment or the general circulation or both. It is vital to check salivary (mucosal) IgA to gliadin to definitively rule in or rule out gluten sensitive enteropathy, clinical or sub-clinical. The salivary anti-gliadin antibody helps to detect earlier stages (sub-clinical) cases of gluten intolerance, while positive humoral antibodies indicate a more advanced and severe gliadin intolerance.

Total Secretory IgA (sIgA): In order to evaluate how well the mucosal barrier first line immune defense is working, it is necessary to look at total secretory IgA. This measurement is used to validate the relevance of the salivary anti-gliadin, IgA result. Suppressed levels of total sIgA may relate to a suppressed IgA anti-gliadin response, even though gluten sensitive enteropathy is present.

Description

Ordering the BioHealth test kit is a simple process

1. Purchase the BioHealth test kit from VitaLiving.com. You never have to pay for shipping.

2. Your BioHealth test kit will be mailed to you.

3. You will also be provided with a Free Return Shipping label to send your samples to the lab.

4. Collect your saliva or stool sample as per directions in the test kit.

5. Mail the test kit using the Free Shipping label.

6. Your test results will be emailed to you within 3 weeks.


This screen uses serum to assess total IgA; IgA and IgG to gliadin, a peptide found in gluten; and anti-transglutaminase IgA, a marker for celiac disease within the humoral immune compartment. It also uses a salivary sample to assess the level of secretory immunoglobulin A (sIgA) and the level of salivary IgA to gliadin within the mucosal immune compartment. This test is designed to assess whether an individual is celiac (overt symptoms) or has subclinical gluten intolerance (non-symptomatic, that is without obvious GI symptoms).

The Markers

Total Serum IgA: Total serum IgA is used to qualify the IgA levels for anti-gliadin and anti-transglutaminase and to rule out compromised systemic immunity. Individuals with Selective IgA deficiency may have a clinical or sub-clinical gluten sensitive enteropathy (GSE) with anti-gliadin IgA and anti-transglutaminase IgA reported within normal ranges.

Anti-Gliadin Antibody, IgA: Gliadin IgA is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgA antibodies in human serum. Detection of these antibodies is an aid in the diagnosis of certain gluten sensitive enteropathies such as celiac disease and herpetiformis. Celiac disease or gluten sensitivity enteropathy is a chronic condition whose main features include inflammation and characteristic histological “flattening” of intestinal mucosa resulting in a malabsorption syndrome.

Anti-Gliadin Antibody, IgG: Gliadin IgG is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgG antibodies in human serum. Detection of these antibodies is an aid in the diagnosis of certain gluten sensitive enteropathies such as celiac disease and herpetiformis. Celiac disease or gluten sensitivity enteropathy is a chronic condition whose main features include inflammation and characteristic histological “flattening” of intestinal mucosa resulting in a malabsorption syndrome.

Anti-Transglutaminase, IgA: Human tissue transglutaminase is an enzyme-linked immunosorbent assay (ELISA) for the detection of IgA antibodies to tissue transglutaminase (endomysium) in human serum. Detection of these antibodies is an aid in diagnosis of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis. Celiac disease and dermatitis herpetiformis, two recognized forms of gluten sensitive enteropathy (GSE) are characterized by chronic inflammation of the intestinal mucosa and flattening of the epithelium or positive “villous atrophy.” Intolerance to gluten (gliadin), the protein found primarily in grains such as wheat, rye and barley causes GSE. Patients with celiac disease may suffer from diarrhea, gastrointestinal problems, anemia, fatigue, psychiatric problems and other diverse side effects or they may be asymptomatic. Dermatitis herpetiformis is a skin disease associated with GSE. All GSE patients have an increased risk of lymphoma. A gluten-free diet controls GSE and associated risks.

Salivary Anti-Gliadin Antibody, IgA: An elevation in this antibody is evidence of mucotoxic reaction to the gliadin polypeptide within the digestive tract. Depending on the overall health of the mucosal barrier and whether or not the gut is “leaky”, gluten sensitive enteropathies can show up either in the mucosal compartment or the general circulation or both. It is vital to check salivary (mucosal) IgA to gliadin to definitively rule in or rule out gluten sensitive enteropathy, clinical or sub-clinical. The salivary anti-gliadin antibody helps to detect earlier stages (sub-clinical) cases of gluten intolerance, while positive humoral antibodies indicate a more advanced and severe gliadin intolerance.

Total Secretory IgA (sIgA): In order to evaluate how well the mucosal barrier first line immune defense is working, it is necessary to look at total secretory IgA. This measurement is used to validate the relevance of the salivary anti-gliadin, IgA result. Suppressed levels of total sIgA may relate to a suppressed IgA anti-gliadin response, even though gluten sensitive enteropathy is present.

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